Your blood doesn't lie

The biomarkers to test for and why

THIS WEEK’S CODE:

💡 The focus   → Biomarkers as the true signal of your longevity habits

⚠️ The impact → You can’t optimize what you don’t measure

The fix        → Build a feedback loop from bloodwork to lifestyle

Read time: 4 minutes

Even with perfect abs, you can still be metabolically broken.

Low inflammation, steady insulin, balanced hormones - these matter more than what’s in the mirror.

Biomarkers give you the full picture: how fast you’re aging, how well your body is recovering, and where silent damage might be hiding.

Most people never test, so they never know. But tracking the right markers turns your daily habits into data.

When you can measure it, you can improve it, this way you’ll know when your lifestyle is actually working.

You can’t improve what you don’t measure

Most chronic diseases brew quietly for years. That’s where biomarkers come in: they provide a measurable window into how your body’s systems are performing.

Markers like fasting insulin can warn of metabolic dysfunction before glucose levels spike.

Elevated hs-CRP can quietly point to chronic inflammation even in people with normal blood pressure and cholesterol.

This is why many high-performance health protocols, from pro athletes to longevity researchers, revolve around quarterly blood panels, in order to catch dysfunction early enough to correct it before it becomes a condition.

What to track and why

1. hs-CRP (High-sensitivity C-reactive protein)

Tracks systemic inflammation. Chronic inflammation is linked to nearly every age-related disease, including cardiovascular disease and Alzheimer’s. Lower is better.

2. Fasting Insulin

Early signal of insulin resistance. More sensitive than fasting glucose or HbA1c for identifying metabolic dysfunction. Ideal range: ~2–5 µIU/mL.

3. ApoB (Apolipoprotein B)

Superior to LDL for assessing cardiovascular risk. ApoB represents the actual number of atherogenic lipoprotein particles - fewer is better.

4. ALT & AST (Liver enzymes)

Elevations can signal fatty liver or early liver stress, even in people without symptoms. Liver health is foundational to metabolic and hormonal balance.

5. Homocysteine

Elevated levels are associated with cognitive decline and cardiovascular risk. It’s also influenced by B vitamin status, making it actionable.

6. Cortisol (AM blood draw or saliva panel)

Helps assess stress response and circadian rhythm health. Chronically high or low levels can disrupt sleep, immunity, and metabolism.

7. Vitamin D (25(OH)D)

Crucial for immune function, bone health, and mood regulation. Many people are deficient without knowing it.

8. Biological Age Tests (e.g. GrimAge, PhenoAge)

These DNA methylation tests assess your biological age vs. calendar age, useful for tracking the cumulative impact of lifestyle interventions over time.

Use feedback as your guide

The goal is to not only collect numbers but also turn them into a personal GPS for your health.

Start with a baseline panel of key biomarkers. Use the results to identify what needs improvement (e.g. lowering inflammation or improving insulin sensitivity).

Adjust your diet, training, supplementation, or sleep based on the data. Then re-test in 3–6 months to track changes.

This loop helps you eliminate guesswork. You’ll know if your fasting protocols or supplement stack are actually moving the needle.

Over time, this builds a habit of high-agency health: you become the experiment, the lab, and the result.

Tracking now and for the future

Most people track steps and calories but ignore the far more valuable signals from their blood.

Although biomarkers measure health, they’re ultimately creating a scoreboard for your habits.

What gets measured gets optimized and over the long haul, that’s what separates lifespan from healthspan.

TLDR TRIO

📈 Biomarkers reveal how your body is really aging.

✅ Track key markers (like hs-CRP, fasting insulin, and vitamin D), adjust your lifestyle, and retest to see what’s working.

⌛ Re-test every 3-6 months and treat your bloodwork like a performance dashboard